刘双江 博士 研究员----中国科学院微生物研究所副所长 环境生物技术中心主任

刘双江

中国科学院微生物研究所副所长 环境生物技术中心主任

电话：86-10-64807423
传真：86-10-64807421
电子邮件：liusj@sun.im.ac.cn
通讯地址：北京市朝阳区大屯路 中国科学院微生物研究所
邮编：100101

教育经历：
1980－1984 河北大学生物系微生物生化专业，本科生
1984－1987 浙江农业大学环境科学系农业微生物专业，硕士研究生
1987－1991 清华大学环境工程系水处理专业， 博士研究生
1995        第18届国际糖生物学及糖生物技术培训班，亚洲分子生物学组织

工作经历：
1991－1995 中科院微生物所，先后任助理研究员、副研究员
1995－1996 德国明斯特大学微生物研究所，高级访问学者、博士后
1996－1997 日本筑波市国立生命工学研究所，高级访问学者
1997－1998 美国James Madison 大学生物系，博士后
1998－2001 赴德国Muenster大学微生物研究所工作
2001年至今   中科院微生物研究所，研究员、博士研究生导师（1）难生物降解有机污染物的微生物降解代谢途径和降解机理的研究
（2）特定区域环境的微生物种群和物质转化
（3）生物质资源的微生物利用技术

研究团队

2007：“国家杰出青年基金”获得者
2000：中国科学院“百人计划”入选者2008

• 1. X-Y Liu, B-J Wang, C-Y Jiang, and S-J Liu. 2008. Ornithinimicrobium pekingense sp. nov., isolated from activated sludge. Int. J. Syst. Evol. Microbiol. 58: 116-119
• 2. Zhi-Pei Liu, Bao-Jun Wang, Xing-Yu Liu, Xin Dai, Ying-Hao Liu and Shuang-Jiang Liu. 2008. Paracoccus marinus sp. nov., isolated from sediment of South China Sea. Int. J. Syst. Evol. Microbiol. 58: 257-261
• 3. Yan Huang, Ke-Xin Zhao, Xi-Hui Shen, Cheng-Ying Jiang, and Shuang-Jiang Liu. 2008. Genetic and biochemical characterization of a 4-hydroxybenzoate hydroxylase from Cornebacterium glutamicum. Appl. Microbiol. Biotechnol. 78:75-83
• 4. Ya-Jun Liu, Pan-Pan Li, Ke-Xin Zhao, Cheng-Ying Jiang, Harold L Drake, Shuang-Jiang Liu. 2008. Corynebacterium glutamicum contains 3-deoxy-D-arabino-heptulosonate 7-phosphate synthases that display novel biochemical features. Appl. Environ. Microbiol. 74:5497-5503.
• 5. Cheng-Ying Jiang, Ying Liu, Yan-Yang Liu, Xiao-Yan You, Xu Guo, and Shuang-Jiang Liu. 2008. Alicyclobacillus ferrooxydans sp. nov. a novel ferrous-oxidizing bacterium from solfataric soil. Submitted to Int. J. Syst. Evol. Microbiol. 58: 2898 - 2903.

2007

• 1. L Liu, C-Y Jiang, X-Y Liu, J-F Wu, J-G Han, S-J Liu. 2007. Engineering plant-microbe symbiosis for rhizoremediation of chloronitroaromatic pollutants with Comamonas sp. strain CNB-1. Environ. Microbiol. 9:465-473
• 2. X-Y Liu, B-J Wang, C-Y Jiang, and S-J Liu. 2007. Micrococcus flavus sp. nov., isolated from activated sludge in a bioreactor. Int. J. Syst. Evol. Microbiol. 57: 66-69
• 3. Y Yang, H-L Cui, P-J Zhou and S-J Liu. 2007. Haloarcula amylolytica sp. nov., an extremely halophilic archaeon isolated from Aibi salt lake in Xin-Jiang, China. Int. J. Syst. Evol. Microbiol. 57: 103-106
• 4. M T Chaudhry, Y Huang, X-H Shen, A Poetsch, C-Y Jiang, S-J Liu. 2007. Genome-wide investigation of aromatic acid transport in Corynebacterium glutamicum. Microbiology (SGM) 153: 857-865
• 5. Z-W Chen, Y-Y Liu, J-F Wu, Q. She, C-Y Jiang and S-J Liu. 2007. Genetic diversity and identification of novel bacterial sulfur oxygenase reductase genes from gold-bioleaching reactor. Appl. Microbiol. Biotechnol. 74:688-698
• 6. Lei Liu, Jian-Feng Wu, Ying-Fei Ma, Sheng-Yue Wang, Guo-Ping Zhao, and Shuang-Jiang Liu. 2007. A novel deaminase involved in chloronitrobenzene and nitrobenzene degradation in Comamonas sp. strain CNB-1. J. Bacteriol. 189:2677-2682
• 7. R. Wang, Y-J Yin, F Wang, M Li, J Feng, H-M Zhang, S-J Liu, W-R Chang. 2007. Crystal structures and site-directed mutagenesis of a mycothiol-dependent enzyme reveal a novel folding and molecular basis for mycothiol-mediated maleylpyruvate isomerization. J. Biol. Chem. 282:16288-15294
• 8. Y-F Ma, J-F Wu, S-Y Wang, C-Y Jiang, Y Zhang, S-W Qi, L Liu, G-P Zhao, S-J Liu. 2007. Nucleotide sequence of plasmid pCNB1 from Comamonas sp. strain CNB-1 reveals novel genetic organization and evolution for 4-chloronitrobenzene degradation. Appl. Environ. Microbiol. 73: 4477-4483
• 9. Yun Zhang, Ying-Fei Ma, Su-Wei Qi, Bo Meng, Muhammad Tausif Chaudhry, Si-Qi Liu, Shuang-Jiang Liu. 2007. Responses to arsenate stress by Comamonas sp. strain CNB-1 at genetic and proteomic levels. Microbiology. 153: 3713-3721
• 10. S-W Qi, M T Chaudhry, Y Zhang, B Meng, Y Huang, K.-X. Zhao, A. Poetsch, C-Y Jiang, S Liu, and S-J Liu. 2007. Comparative proteomes of Corynebacterium glutamicum grown on aromatic compounds revealed novel proteins involved in aromatic degradation and a clear link between aromatic catabolism and gluconeogenesis via fructose-1,6-bisphosphatase. Proteomics 7:3775-87

2006

• 1. Jie Feng, Hong-Can Liu, Jin-Fang Chu, Ji-An Tang, Shuang-Jiang Liu 2006. Genetic cloning and functional expression in Escherichia coli of an archaerhodopsin gene from Halorubrum xinjiangense. Extremophiles. 10: 29-33
• 2. C.-Y. Jiang, X. Dai, B.-J. Wang, Y.-G. Zhou, and S.-J. Liu. 2006. Roseomonas lacus sp. nov., a bacterium isolated from freshwater lake sediment. Int. J. Syst. Evol. Microbiol. 56: 25-28
• 3. X. Dai, B.-J. Wang, Q.-X. Yang, N.-Z. Jiao and S.-J. Liu. 2006. Yangia pacifica gen. nov., sp. nov., a novel member of the Roseobacter clade from coastal sediment of East China Sea, Int. J. Syst. Evol. Microbiol. 56: 529-533
• 4. J-F. Wu, C-Y Jiang, B-J Wang, Y-F Ma, Z-P Liu, S-J Liu 2006. A novel partial reductive pathway for 4-chloronitrobenzene and nitrobenzene degradation in Comamonas strain CNB-1. Appl. Environ. Microbiol. 72: 1759-1765
• 5. J Feng, Y Che, J Milse, Y-J Yin, L Liu, C Rückert, X-H Shen, S-W Qi, J Kalinowski, S-J Liu. 2006. The gene ncgl2918 encodes a novel maleylpyruvate isomerase that needs mycothiol as cofactor and links mycothiol biosynthesis and gentisate assimilation in Corynebacterium glutamicum. J. Biol. Chem. 281: 10778-10785
• 6. H-L Cui, D Tohty, P-J Zhou, S-J Liu. 2006. Haloterrigena longa sp. nov. and Haloterrigena limicola sp. nov., two extremely halophilic archaea isolated from salt lake. Int. J. Syst. Evol. Microbiol. 56: 1837-1840.
• 7. X-Y Liu, B-J Wang, C-Y Jiang, and S-J Liu. 2006. Paracoccus sulfuroxidans sp. nov., a sulfur oxidizer from activated sludge. Int. J. Syst. Evol. Microbiol. 56: 2693-2695
• 8. Y Huang, K-X Zhao, X-H Shen, M T Chaudhry, C-Y Jiang, S-J Liu. 2006. Genetic characterization of resorcinol catabolic pathway in Corynebacterium glutamicum. Appl. Environ. Microbiol. 72:7238-7245

2005

• 1. J-F Wu, C-W Sun, C-Y Jiang, Z-P Liu, and S-J Liu 2005. A novel 2-aminophenol 1,6-dioxygenase involved in the degradation of p-chloronitrobenzene by Comamonas strain CNB-1: purification, properties, genetic cloning and expression in Escherichia coli. Arch. Microbiol. 183:1-8.
• 2. X-H Shen and S-J Liu 2005. Key enzymes of the protocatechuate branch of the b–ketoadipate pathway for aromatic degradation in Corynebacterium glutamicum. Science in China. 48:241-249.
• 3. Z-W Chen, C-Y Jiang, Q She, S-J Liu, P-J Zhou 2005. Key role of Cysteine Residues in catalysis and Subcellular Localization of Sulfur Oxygenase Reductase of Acidianus tengchongensis. Appl. Environ. Microbiol. 2005 71: 621-628
• 4. X-H Shen, C-Y Jiang, Y Huang, Z-P Liu, S-J Liu 2005. Functional identification of novel genes involved in the glutathione-independent gentisate pathway in Corynebacterium glutamicum. Appl. Environ. Microbiol. 2005 71: 3442-3452
• 5. X. Dai, Y.-N. Wang, B.-J. Wang, S.-J. Liu and Y. G. Zhou 2005. Planomicrobium chinense sp. nov., isolated from coastal sediment, and transfer of Planococcus psychrophilus and Planococcus alkanoclasticus to Planomicrobium as Planomicrobium psychrophilum comb. nov. and Planomicrobium alkanoclasticum comb. nov. Int. J. Syst. Evol. Microbiol. 55: 699-702.
• 6. Zhi-Pei Liu, Bao-Jun Wang, Ying-Hao Liu, and Shuang-Jiang Liu 2005. Novosphingobium taihuense sp. nov. a novel aromatic compound-degrading bacterium isolated from Taihu Lake, China. Int. J. Syst. Evol. Microbiol. 55: 1229 - 1232.
• 7. Zhi-Pei Liu, Bao-Jun Wang, Shuang-Jiang Liu and Ying-Hao Liu 2005. Asticcacaulis taihuensis sp. nov., a new stalked bacterium isolated from Taihu Lake, China. Int. J. Syst. Evol. Microbiol. 55: 1239 - 1242.
• 8. Xue-Wei Xu, Pei-Gen Ren, Shuang-Jiang Liu, Min Wu, and Pei-Jin Zhou 2005 Natrinema altunense sp. nov., an extremely halophilic archaeon isolated from a salt lake in Altun Mountain in Xinjiang, China. Int J Syst Evol Microbiol, 55: 1311 - 1314.

2004

• 1. J. Feng, P. Zhou, and S.-J. Liu 2004. Halorubrum xingjiangense sp. nov., a novel halophile isolated from saline lakes in China. Int. J. Syst. Evol. Microbiol. 54:1789-1791 
• 2. X. Shen, Z. Liu, S.-J. Liu 2004. Functional identification of the gene locus (ncg12319) and characterization of catechol 1,2-dioxygenase in Corynebacterium glutamicum Biotechnol. Lett. 26:575-580.
• 3. Y.-T. Hu, P.-J. Zhou, Y.-G. Zhou, Z.-H. Liu and S.-J. Liu 2004. Saccharothrix xinjiangensis sp. nov., a pyrene-degrading actinomycete isolated from Tianchi lake, Xinjiang, China. Int. J. Syst. Evol. Microbiol. 54:2091-2094.

2003

• 1. Demin Zhang, Huifang Yang, Wei Zhang, Zhiyong Huang, and Shuang-Jiang Liu. Rhodocista pekingensis sp. nov., a cyst-forming phototrophic bacterium from a municipal wastewater treatment plant. Int J Syst Evol Microbiol, 2003; 53: 1111 - 1114.
• 2. Cui-wei Sun, Zhi-wei Chen, Zheng-guo He, Pei-jin Zhou, Shuang-Jiang Liu. 2003. Purification and properties of the sulfur oxygenase/reductase from the acidothermophilic archaeon, Acidianus strain S5. Extremophiles 7, 131 - 134 

2002

• 1. D. Zhang, H. Yang, Z. Huang, W. Zhang, and S. J. Liu. Rhodopseudomonas faecalis sp. nov., a phototrophic bacterium isolated from an anaerobic reactor that digests chicken faeces. Int J Syst Evol Microbiol, 2002; 52: 2055 - 2060.
• 2. Z. Liu, H. Yang, Z. Huang, P. Zhou, and S.-J. Liu. Degradation of aniline by newly isolated, extremely aniline-tolerant Delftia sp. AN3. Appl. Microbiol. Biotechnol. 2002, 58:679-682.
• 3. Lutke-Eversloh, T; Fischer, A; Remminghorst, U; Kawada, J; Marchessault, RH; Bogershausen, A; Kalwei, M; Eckert, H; Reichelt, R; Liu, SJ; Steinbuchel, A: Biosynthesis of novel thermoplastic polythioesters by engineered Escherichia coli Nature Materials, 2002, 1:236-240

2000

• 1. Z.G. He, Y. Li,  P. Zhou, S.-J. Liu. Cloning and heterologous expression of a sulfur oxygenase/reductase from the thermoacidophilic archaeon, Acidianus sp. S5 in Escherichia coli FEMS Microbiol. Lett. 2000, 193: 217-221
• 2. Shuang-jiang Liu and Alexander Steinbüchel A Novel Genetically Engineered Pathway for Synthesis of poly (hydroxyalkanoic acid) in Escherichia coli Applied Environmental Microbiology, 2000, (66): 739-743
• 3. S.-J. Liu . A. Steinbüchel Exploitation of butyrate kinase and phosphotransbutyrylase from Clostridium acetobutylicum for the in vitro biosynthesis of poly (hydroxyalkanoic acid) Appl Microbiol Biotechnol, 2000, (53): 545-552 1．Shuang-Jiang Liu. 2008. Chapter 17. Archaeal and bacterial sulfur oxygenase reductase: genetic diversity and physiological function. In: Microbial sulfur metabolism. C. Dahl and C. G. Friedrich (eds). Springer 2008. Page 217-224

• 2．Shuang-Jiang Liu and Harold L Drake (editors). 2008. Microbes and the environment: Perspectives and challenges. Science Press